| ncRNA name | TLR3 siRNA |
| ncRNA Category | siRNA |
| Disease name | age-related macular degeneration (AMD) |
| Species | Homo sapiens |
| Tissues/Cell_line | human RPE cell line ARPE-19 |
| Methods | qRT-PCR, siRNA transfection, cell death assay |
| Expression pattern | associated |
| Functional description | The authors demonstrate that the expression of proinflammatory cytokines and chemokines in RPE cells depends on the activation of TLR3. The induction of downstream gene expression is blocked by siRNA specific for TLR3 and alkylphosphocholines. |
| PubMed ID | 21715345 |
| Year | 2011 |
| Title | Inhibition of TLR3-mediated proinflammatory effects by Alkylphosphocholines in human retinal pigment epithelial cells. |
| Drug-related ncRNA | NO |
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